… and penicillin nonsusceptibility in Streptococcus pneumoniae (… We show that the frequency
of penicillin resistance in S. … other is temporal: Although, in individual countries, resistance …

… in pneumococcal resistance to both penicillin and macrolides between 2019 and 2020. The
… dynamics of antibiotic resistance in S. pneumoniae, we propose a mathematical model that …

… pneumonias and bloodstream infections, because it will be unlikely to induce penicillin
resistance, and the use of total antibiotics and cephalosporins is more strongly associated with a …

… resistant to penicillin) but more pronounced for PCV20 (serotypes 15BC and 11A are among
the most carried and often antibiotic resistant). … Using a segmented regression model, we …

… , Staphylococcus aureus, and Streptococcus pneumoniae temporally and globally. Among
… In the search for new antimicrobial agents, the microbial bioactive compounds are nowhere …

… Mathematical models simulating the effects of pneumococcal vaccination on AMR have …
of co-colonisation, exposure to antibiotics, as well as the cost of resistance and country-specific …

… Since the discovery of penicillin, antibiotics have contributed … the temporal relationship
between antibiotic intake and … The number of knots was decided by assessing the fit of the model …

… models to test which aggregator is the best predictor of the three traits of interest and found
that models … HGT and resistance (7, 12–14) spanned different spatial and temporal scales …

… models to evaluate the seasonal use–resistance relationship … on antibiotics with wintertime
peaks in use (eg, penicillins, … in use, best correlated temporally with use of winter peaking …

… or resistance to each antibiotic class using random-effects meta-regression models, …
Committee on Antimicrobial Susceptibility Testing), we defined penicillin susceptibility according to …